Large 16:9 monitors have height issues...

With the default 16:9 ratio for TV display panels, desk use creates more of an issue with the height rather than the width. To counter this you really want the bottom pixels of the display area at the lowest point possible to be visible by the user, and this requires counter-sinking the stand into the desk:

So this results in a desk layout something like this:

I'm sure this could be done more elegantly but you get the idea.  An alternative would be to cantilever a VESA stand from the back of the desk with the bottom bezel below the back edge of the desk, but that would involve a heavy bit of kit hanging off the back of the desk.
I wonder whether manufacturers think of patenting obvious ideas like this. Wouldn't surprise me...